9 research outputs found
Content Addressable Memories and Transformable Logic Circuits Based on Ferroelectric Reconfigurable Transistors for In-Memory Computing
As a promising alternative to the Von Neumann architecture, in-memory
computing holds the promise of delivering high computing capacity while
consuming low power. Content addressable memory (CAM) can implement pattern
matching and distance measurement in memory with massive parallelism, making
them highly desirable for data-intensive applications. In this paper, we
propose and demonstrate a novel 1-transistor-per-bit CAM based on the
ferroelectric reconfigurable transistor. By exploiting the switchable polarity
of the ferroelectric reconfigurable transistor, XOR/XNOR-like matching
operation in CAM can be realized in a single transistor. By eliminating the
need for the complementary circuit, these non-volatile CAMs based on
reconfigurable transistors can offer a significant improvement in area and
energy efficiency compared to conventional CAMs. NAND- and NOR-arrays of CAMs
are also demonstrated, which enable multi-bit matching in a single reading
operation. In addition, the NOR array of CAM cells effectively measures the
Hamming distance between the input query and stored entries. Furthermore,
utilizing the switchable polarity of these ferroelectric Schottky barrier
transistors, we demonstrate reconfigurable logic gates with NAND/NOR dual
functions, whose input-output mapping can be transformed in real-time without
changing the layout. These reconfigurable circuits will serve as important
building blocks for high-density data-stream processors and reconfigurable
Application-Specific Integrated Circuits (r-ASICs). The CAMs and transformable
logic gates based on ferroelectric reconfigurable transistors will have broad
applications in data-intensive applications from image processing to machine
learning and artificial intelligence
Low-Thermal-Budget Ferroelectric Field-Effect Transistors Based on CuInP2S6 and InZnO
In this paper, we demonstrate low-thermal-budget ferroelectric field-effect
transistors (FeFETs) based on two-dimensional ferroelectric CuInP2S6 (CIPS) and
oxide semiconductor InZnO (IZO). The CIPS/IZO FeFETs exhibit non-volatile
memory windows of ~1 V, low off-state drain currents, and high carrier
mobilities. The ferroelectric CIPS layer serves a dual purpose by providing
electrostatic doping in IZO and acting as a passivation layer for the IZO
channel. We also investigate the CIPS/IZO FeFETs as artificial synaptic devices
for neural networks. The CIPS/IZO synapse demonstrates a sizeable dynamic ratio
(125) and maintains stable multi-level states. Neural networks based on
CIPS/IZO FeFETs achieve an accuracy rate of over 80% in recognizing MNIST
handwritten digits. These ferroelectric transistors can be vertically stacked
on silicon CMOS with a low thermal budget, offering broad applications in
CMOS+X technologies and energy-efficient 3D neural networks
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic etiology, which is partially shared and partially distinct from that of related psychiatric disorders. Methods We conducted a genome-wide association study (GWAS) of 29,782 suicide attempt (SA) cases and 519,961 controls in the International Suicide Genetics Consortium (ISGC). The GWAS of SA was conditioned on psychiatric disorders using GWAS summary statistics via multitrait-based conditional and joint analysis, to remove genetic effects on SA mediated by psychiatric disorders. We investigated the shared and divergent genetic architectures of SA, psychiatric disorders, and other known risk factors. Results Two loci reached genome-wide significance for SA: the major histocompatibility complex and an intergenic locus on chromosome 7, the latter of which remained associated with SA after conditioning on psychiatric disorders and replicated in an independent cohort from the Million Veteran Program. This locus has been implicated in risk-taking behavior, smoking, and insomnia. SA showed strong genetic correlation with psychiatric disorders, particularly major depression, and also with smoking, pain, risk-taking behavior, sleep disturbances, lower educational attainment, reproductive traits, lower socioeconomic status, and poorer general health. After conditioning on psychiatric disorders, the genetic correlations between SA and psychiatric disorders decreased, whereas those with nonpsychiatric traits remained largely unchanged. Conclusions Our results identify a risk locus that contributes more strongly to SA than other phenotypes and suggest a shared underlying biology between SA and known risk factors that is not mediated by psychiatric disorders.Peer reviewe